1453116-06-7

1453116-06-7 structure

Name: NaPi2b-IN-1
Chemical Name: NaPi2b-IN-1
CAS Number: 1453116-06-7
Molecular Formula: C₄₄H₅₈ClF₃N₄O₁₁S
Molecular Weight: 943.46
Catalog: Research Areas Others
Create Date: 2022-04-13 08:47:34
Modify Date: 2025-08-26 18:46:06
NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia[1].

Name	NaPi2b-IN-1

Description	NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Maemoto M, et al. Discovery of Gut-Restricted Small-Molecule Inhibitors of Intestinal Sodium-Dependent Phosphate Transport Protein 2b (NaPi2b) for the Treatment of Hyperphosphatemia. J Med Chem. 2022;65(3):1946-1960.

Molecular Formula	C₄₄H₅₈ClF₃N₄O₁₁S
Molecular Weight	943.46