OP-0595

Modify Date: 2025-08-22 11:35:05

OP-0595 structure	Common Name	OP-0595
	CAS Number	1452458-86-4	Molecular Weight	324.31
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₆N₄O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of OP-0595

Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and class C β-lactamases. Nacubactam (OP0595 free acid) acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs[1][2].

Name	Nacubactam

Description	Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and class C β-lactamases. Nacubactam (OP0595 free acid) acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	non-β-lactam-β-lactamase[1]
References	[1]. Monogue ML, et al. In Vivo Efficacy of Meropenem with a Novel Non-β-Lactam-β-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model. Antimicrob Agents Chemother. 2018 Aug 27;62(9). [2]. Livermore DM, et al. Activity of OP0595/β-lactam combinations against Gram-negative bacteria with extended-spectrum, AmpC and carbapenem-hydrolysing β-lactamases. J Antimicrob Chemother. 2015 Nov;70(11):3032-41.

Molecular Formula	C₉H₁₆N₄O₇S
Molecular Weight	324.31
InChIKey	RSBPYSTVZQAADE-RQJHMYQMSA-N
SMILES	NCCONC(=O)C1CCC2CN1C(=O)N2OS(=O)(=O)O
Storage condition	-20°C

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: OP-0595
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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OP-0595

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OP-0595 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.