Sodium taurocholate

Modify Date: 2024-01-02 15:52:55

Sodium taurocholate structure	Common Name	Sodium taurocholate
	CAS Number	145-42-6	Molecular Weight	537.685
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₄NNaO₇S	Melting Point	230 °C
	MSDS	Chinese USA	Flash Point	N/A

Use of Sodium taurocholate

Taurocholic acid sodium (Sodium taurocholate; N-Choloyltaurine sodium) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Immunoregulation effect[1].

Name	sodium taurocholate
Synonym	More Synonyms

Description	Taurocholic acid sodium (Sodium taurocholate; N-Choloyltaurine sodium) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Immunoregulation effect[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	Microbial Metabolite Human Endogenous Metabolite
References	[1]. Caiyun Wang, et al. Effects of taurocholic acid on immunoregulation in mice. Int Immunopharmacol. 2013 Feb;15(2):217-22.

Melting Point	230 °C
Molecular Formula	C₂₆H₄₄NNaO₇S
Molecular Weight	537.685
Exact Mass	537.273621
PSA	155.37000
LogP	3.49720
Index of Refraction	23 ° (C=3, H2O)
Water Solubility	> 250 g/L (20 ºC)

Sodium taurocholate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WX0400000

CHEMICAL NAME :: Taurine, N-choloyl-, sodium salt

CAS REGISTRY NUMBER :: 145-42-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C26-H44-N-O7-S.Na

MOLECULAR WEIGHT :: 537.76

WISWESSER LINE NOTATION :: L E5 B666TJ A1 DQ E1 FY1&2VM2SWO KQ OQ &-NA- &42/32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 110 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 1 gm/kg

REFERENCE :: JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 78,32,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80529 No. of Facilities: 126 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 3026 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80529 No. of Facilities: 52 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 741 (estimated) No. of Female Employees: 544 (estimated)

Risk Phrases	R36/37/38
Safety Phrases	S26-S36/37/39-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	WX0400000

Taurine

CAS#:107-35-7

cholic acid

CAS#:81-25-4

~89%

Sodium taurocholate

CAS#:145-42-6

Literature: Venturoni, Francesco; Gioiello, Antimo; Sardella, Roccaldo; Natalini, Benedetto; Pellicciari, Roberto Organic and Biomolecular Chemistry, 2012 , vol. 10, # 20 p. 4109 - 4115

Precursor 2
CAS#:107-35-7 Taurine CAS#:81-25-4 cholic acid
DownStream 3
CAS#:107-35-7 Taurine CAS#:81-25-4 cholic acid CAS#:75-65-0 tert-Butanol

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Taurine, N-choloyl-, monosodium salt

monosodium N-choloyltaurinate

sodium N-choloyltaurinate

Sodium 2-({(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl}amino)ethanesulfonate

MFCD00013050

ethanesulfonic acid, 2-[[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

Taurocholic Acid Sodium Salt from Bovine Bile

froM Bovine Bile

taurocholatesodiumsalt

Sodium 2-{[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate

Ethanesulfonic acid, 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

taurocholic acid sodium salt

Sodium taurocholate

taurocholatesodium

Bile Salts (10 g)

TAUROCHOLIC ACID NA-SALT

2-{[(3α,5β,7α,8ξ,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]amino}éthanesulfonate de sodium

taurocholate sodium

taurocholate sodiuM sal

Natrium-2-({(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl}amino)ethansulfonat

Sodium Taurocholate from Bovine Bile

Natrium-2-{[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}ethansulfonat

Taurocholic acid

Monosodium 2-(((3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)ethanesulfonate

EINECS 205-653-7

Sodium 2-{[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate

taurocholate sodium salt

taurochlolic acid sodium salt

Ethanesulfonic acid, 2-(((3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)-, monosodium salt

Taurocholic sodium

2-({(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-diméthylhexadécahydro-1H-cyclopenta[a]phénanthrén-17-yl]pentanoyl}amino)éthanesulfonate de sodium

Taurine, N-choloyl-, sodium salt

Sodium taurocholate hydrate

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Sodium taurocholate
Price: ￥188.0/1g ￥688.0/5g ￥208.0/20mg
Purity: 95.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Sodium taurocholate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Sodium taurocholate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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