Bis-PEG4-TFP ester

Modify Date: 2024-01-15 14:30:50

Bis-PEG4-TFP ester Structure
Bis-PEG4-TFP ester structure
Common Name Bis-PEG4-TFP ester
CAS Number 1446282-42-3 Molecular Weight 590.414
Density 1.4±0.1 g/cm3 Boiling Point 572.7±50.0 °C at 760 mmHg
Molecular Formula C24H22F8O8 Melting Point N/A
MSDS N/A Flash Point 289.0±25.0 °C

 Use of Bis-PEG4-TFP ester


Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis(2,3,5,6-tetrafluorophenyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate
Synonym More Synonyms

 Bis-PEG4-TFP ester Biological Activity

Description Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 572.7±50.0 °C at 760 mmHg
Molecular Formula C24H22F8O8
Molecular Weight 590.414
Flash Point 289.0±25.0 °C
Exact Mass 590.118713
LogP 3.76
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.474

 Synonyms

Bis(2,3,5,6-tetrafluorophenyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate
4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, bis(2,3,5,6-tetrafluorophenyl) ester
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Bis-PEG4-TFP ester suppliers

Bis-PEG4-TFP ester price