1426164-53-5
1426164-53-5 structure
- Name: Bis-Mal-Lysine-PEG4-TFP ester
- Chemical Name: Bis-Mal-Lysine-PEG4-TFP ester
- CAS Number: 1426164-53-5
- Molecular Formula: C37H45F4N5O13
- Molecular Weight: 843.773
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-16 11:01:50
- Modify Date: 2024-01-14 12:23:32
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Bis-Mal-Lysine-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Bis-Mal-Lysine-PEG4-TFP ester |
|---|---|
| Synonyms |
Bis-MAL-Lysine-dPEG(R)4-TFP ester
2,3,5,6-Tetrafluorophenyl 1-({N2,N6-bis[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]lysyl}amino)-3,6,9,12-tetraoxapentadecan-15-oate MFCD28385461 4,7,10,13-Tetraoxa-16,23-diazahexacosan-1-oic acid, 26-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-18-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]-17,24-dioxo-, 2,3,5,6-tetrafluorophenyl ester |
| Description | Bis-Mal-Lysine-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1012.1±65.0 °C at 760 mmHg |
| Molecular Formula | C37H45F4N5O13 |
| Molecular Weight | 843.773 |
| Flash Point | 565.9±34.3 °C |
| Exact Mass | 843.294983 |
| LogP | -0.59 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.535 |