2408741-87-5

2408741-87-5 structure
2408741-87-5 structure
  • Name: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
  • Chemical Name: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
  • CAS Number: 2408741-87-5
  • Molecular Formula: C78H134F4N4O35
  • Molecular Weight: 1763.90
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:51:06
  • Modify Date: 2024-01-08 08:28:22
  • Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
Synonyms MFCD28505507
Description Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C78H134F4N4O35
Molecular Weight 1763.90
Hazard Codes Xi