Thiol-PEG3-Boc

Modify Date: 2024-01-02 17:01:11

Thiol-PEG3-Boc Structure
Thiol-PEG3-Boc structure
Common Name Thiol-PEG3-Boc
CAS Number 1446282-39-8 Molecular Weight 294.41
Density N/A Boiling Point N/A
Molecular Formula C13H26O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thiol-PEG3-Boc


Thiol-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thiol-PEG3-t-butyl ester
Synonym More Synonyms

 Thiol-PEG3-Boc Biological Activity

Description Thiol-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H26O5S
Molecular Weight 294.41

 Synonyms

THIOL-PEG3-T-BUTYL ESTER
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