Thiol-PEG3-acetic acid
Modify Date: 2025-08-25 09:14:15
Thiol-PEG3-acetic acid structure
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Common Name | Thiol-PEG3-acetic acid | ||
|---|---|---|---|---|
| CAS Number | 200291-35-6 | Molecular Weight | 224.27500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H16O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thiol-PEG3-acetic acidThiol-PEG3-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Thiol-PEG3-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C8H16O5S |
|---|---|
| Molecular Weight | 224.27500 |
| Exact Mass | 224.07200 |
| PSA | 103.79000 |
| LogP | 0.05060 |
| InChIKey | OQVCAAVSSRTKKR-UHFFFAOYSA-N |
| SMILES | O=C(O)COCCOCCOCCS |
| Acetic acid,[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy] |