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1360716-43-3

1360716-43-3 structure
1360716-43-3 structure
  • Name: Thiol-PEG3-phosphonic acid ethyl ester
  • Chemical Name: Thiol-PEG3-phosphonic acid ethyl ester
  • CAS Number: 1360716-43-3
  • Molecular Formula: C12H27O6PS
  • Molecular Weight: 330.38
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:59:12
  • Modify Date: 2022-02-06 21:39:56
  • Thiol-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Thiol-PEG3-phosphonic acid ethyl ester
Description Thiol-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H27O6PS
Molecular Weight 330.38