IMPDH2-IN-2

Modify Date: 2025-08-25 12:17:11

IMPDH2-IN-2 Structure
IMPDH2-IN-2 structure
Common Name IMPDH2-IN-2
CAS Number 1434517-02-8 Molecular Weight 428.27
Density N/A Boiling Point N/A
Molecular Formula C21H15Cl2N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IMPDH2-IN-2


IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent[1].

 Names

Name IMPDH2-IN-2

 IMPDH2-IN-2 Biological Activity

Description IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent[1].
Related Catalog
Target

IMPDH[1]

References

[1]. Chacko S, et al. Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents [published correction appears in J Med Chem. 2021 Dec 23;64(24):18233-18234]. J Med Chem. 2018;61(11):4739-4756.

 Chemical & Physical Properties

Molecular Formula C21H15Cl2N3O3
Molecular Weight 428.27
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