1434517-02-8

1434517-02-8 structure

Name: IMPDH2-IN-2
Chemical Name: IMPDH2-IN-2
CAS Number: 1434517-02-8
Molecular Formula: C₂₁H₁₅Cl₂N₃O₃
Molecular Weight: 428.27
Catalog: Research Areas Cancer
Create Date: 2022-03-26 12:37:12
Modify Date: 2025-08-25 12:17:11
IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent[1].

Name	IMPDH2-IN-2

Description	IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	IMPDH[1]
References	[1]. Chacko S, et al. Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents [published correction appears in J Med Chem. 2021 Dec 23;64(24):18233-18234]. J Med Chem. 2018;61(11):4739-4756.

Molecular Formula	C₂₁H₁₅Cl₂N₃O₃
Molecular Weight	428.27