UCSF924
Modify Date: 2024-01-10 06:32:55
UCSF924 structure
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Common Name | UCSF924 | ||
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| CAS Number | 1434515-70-4 | Molecular Weight | 322.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H22N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UCSF924UCSF924 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has a high-affinity with a Ki value of 3 nM for DRD4 and shows no measurable affinity for D2, D3 or the F261V/L328F D4 mutant. UCSF924 is a 7.4-fold bias toward arrestin over Gαi/o signaling, referenced to quinpirole[1]. |
| Name | UCSF924 |
|---|
| Description | UCSF924 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has a high-affinity with a Ki value of 3 nM for DRD4 and shows no measurable affinity for D2, D3 or the F261V/L328F D4 mutant. UCSF924 is a 7.4-fold bias toward arrestin over Gαi/o signaling, referenced to quinpirole[1]. |
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| Related Catalog | |
| Target |
Ki: 3 nM (dopamine D4 receptor)[1] |
| References |
| Molecular Formula | C20H22N2O2 |
|---|---|
| Molecular Weight | 322.40 |