BMS-962212

Modify Date: 2024-01-03 18:08:31

BMS-962212 Structure
BMS-962212 structure
Common Name BMS-962212
CAS Number 1430114-34-3 Molecular Weight 659.07
Density N/A Boiling Point N/A
Molecular Formula C32H28ClFN8O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-962212


BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1].

 Names

Name BMS-962212

 BMS-962212 Biological Activity

Description BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1].
Related Catalog
References

[1]. Perera V, et al. First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects. Br J Clin Pharmacol. 2018 May;84(5):876-887.

 Chemical & Physical Properties

Molecular Formula C32H28ClFN8O5
Molecular Weight 659.07
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