FGIN-1-27
FGIN-1-27 structure
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Common Name | FGIN-1-27 | ||
|---|---|---|---|---|
| CAS Number | 142720-24-9 | Molecular Weight | 436.60500 | |
| Density | 1.073g/cm3 | Boiling Point | 608.3ºC at 760mmHg | |
| Molecular Formula | C28H37FN2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 321.7ºC | |
Use of FGIN-1-27FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions[1]. |
| Name | 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide |
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| Synonym | More Synonyms |
| Description | FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions[1]. |
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| Related Catalog | |
| References |
| Density | 1.073g/cm3 |
|---|---|
| Boiling Point | 608.3ºC at 760mmHg |
| Molecular Formula | C28H37FN2O |
| Molecular Weight | 436.60500 |
| Flash Point | 321.7ºC |
| Exact Mass | 436.28900 |
| PSA | 36.10000 |
| LogP | 7.50570 |
| Vapour Pressure | 9.6E-15mmHg at 25°C |
| Index of Refraction | 1.562 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
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Design, synthesis and structure-affinity relationships of aryloxyanilide derivatives as novel peripheral benzodiazepine receptor ligands.
Bioorg. Med. Chem. 12(2) , 423-38, (2004) Since the peripheral benzodiazepine receptor (PBR) has been primarily found as a high-affinity binding site for diazepam in rat kidney, numerous studies of it have been performed. However, the physiol... |
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Translocator protein (18 kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis.
Biochem. Pharmacol. 97 , 99-110, (2015) As a major regulator in obesity and its associated metabolic complications, the proper functioning of adipocytes is crucial for health maintenance, thus serving as an important target for the developm... |
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Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway.
Br. J. Cancer 89(3) , 564-72, (2003) Specific ligands of the peripheral benzodiazepine receptor (PBR) are known to induce apoptosis and cell cycle arrest in oesophageal cancer cells. However, the underlying mechanisms are still unknown. ... |
| MFCD00467704 |
| Fgin 1 27 |
| Lopac-D-8555 |
| Tocris-0658 |
| N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide |