145040-29-5

145040-29-5 structure

Name: FGIN-1-43
Chemical Name: 2-[5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
CAS Number: 145040-29-5
Molecular Formula: C₂₈H₃₆Cl₂N₂O
Molecular Weight: 487.50
Catalog: Research Areas Neurological Disease
Create Date: 2017-06-30 05:04:50
Modify Date: 2025-09-18 18:41:05
FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids). FGIN 1-43 enhances the transmission of GABA by inducing the production of neurosteroids, which can be used for research on anti-anxiety[1].

Name	2-[5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
Synonyms	FGIN-1-43 Tocris-0659

Description	FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids). FGIN 1-43 enhances the transmission of GABA by inducing the production of neurosteroids, which can be used for research on anti-anxiety[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Guillon J, et al. Synthesis and preliminary behavioural evaluation in mice of new 3-aryl-3-pyrrol-1-ylpropanamides, analogues of FGIN-1-27 and FGIN-1-43. J Pharm Pharmacol. 2001 Nov;53(11):1561-8.