SGK1-IN-2

Modify Date: 2025-11-29 12:27:23

SGK1-IN-2 Structure
SGK1-IN-2 structure
Common Name SGK1-IN-2
CAS Number 1426214-64-3 Molecular Weight 435.29
Density N/A Boiling Point N/A
Molecular Formula C17H12Cl2N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SGK1-IN-2


SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration[1].

 Names

Name SGK1-IN-2

 SGK1-IN-2 Biological Activity

Description SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration[1].
Related Catalog
References

[1]. Halland N, et al. Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors. ACS Med Chem Lett. 2014 Oct 23;6(1):73-8.

 Chemical & Physical Properties

Molecular Formula C17H12Cl2N6O2S
Molecular Weight 435.29
InChIKey RTERCHJCWXQPSS-UHFFFAOYSA-N
SMILES Nc1[nH]nc2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4Cl)cc3)cnc12
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