H2N-PEG4-Hydrazide

Modify Date: 2024-01-02 10:59:24

H2N-PEG4-Hydrazide structure	Common Name	H2N-PEG4-Hydrazide
	CAS Number	1425973-15-4	Molecular Weight	279.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₂₅N₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of H2N-PEG4-Hydrazide

H2N-PEG4-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	H2N-PEG4-Hydrazide

Description	H2N-PEG4-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₁H₂₅N₃O₅
Molecular Weight	279.33