1425973-15-4

1425973-15-4 structure

1425973-15-4 structure

Name: H2N-PEG4-Hydrazide
Chemical Name: H2N-PEG4-Hydrazide
CAS Number: 1425973-15-4
Molecular Formula: C₁₁H₂₅N₃O₅
Molecular Weight: 279.33
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:58:38
Modify Date: 2024-01-02 10:59:24
H2N-PEG4-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	H2N-PEG4-Hydrazide

Description	H2N-PEG4-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₁H₂₅N₃O₅
Molecular Weight	279.33