Boc-Ala-Ala-D-Trp-Phe-D-Pro-Pro-NleNH2 structure
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Common Name | Boc-Ala-Ala-D-Trp-Phe-D-Pro-Pro-NleNH2 | ||
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CAS Number | 141663-86-7 | Molecular Weight | 900.07400 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C47H65N9O9 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Boc-Ala-Ala-D-Trp-Phe-D-Pro-Pro-NleNH2GR 87389 is a potent NK2 receptor antagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra[1][2]. |
Name | Boc-Ala-Ala-D-Trp-Phe-D-Pro-Pro-NleNH2 |
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Synonym | More Synonyms |
Description | GR 87389 is a potent NK2 receptor antagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra[1][2]. |
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Related Catalog | |
Target |
NK2 |
In Vitro | GR 87389 是一种非肽和肽速激肽拮抗剂,对海马、膀胱和十二指肠的 Ki 值分别为 4.0、5.2 和 14 nM[1]。 GR 87389 (30-300 nM) 拮抗 GA 64349 诱导的人类逼尿肌、前列腺和前列腺尿道平滑肌条收缩[2]。 |
References |
Molecular Formula | C47H65N9O9 |
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Molecular Weight | 900.07400 |
Exact Mass | 899.49100 |
PSA | 254.23000 |
LogP | 5.01350 |
boc-ala-ala-d-trp-phe-d-pro-pro-nle-nh2 |