Azide-PEG5-Boc

Modify Date: 2025-08-20 16:56:11

Azide-PEG5-Boc Structure
Azide-PEG5-Boc structure
Common Name Azide-PEG5-Boc
CAS Number 1415800-41-7 Molecular Weight 391.460
Density N/A Boiling Point N/A
Molecular Formula C17H33N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azide-PEG5-Boc


Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azide-PEG5-t-butyl ester
Synonym More Synonyms

 Azide-PEG5-Boc Biological Activity

Description Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H33N3O7
Molecular Weight 391.460
Exact Mass 391.231842
LogP 0.27
InChIKey RGXALMUKZGZJKF-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-]

 Synonyms

2-Methyl-2-propanyl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-azido-, 1,1-dimethylethyl ester
MFCD22683303
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