BRD6688
Modify Date: 2024-01-06 07:38:11
BRD6688 structure
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Common Name | BRD6688 | ||
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| CAS Number | 1404562-17-9 | Molecular Weight | 282.340 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 528.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C16H18N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 273.3±30.1 °C | |
Use of BRD6688BRD6688 is a selective HDAC2 inhibitor. BRD6688 increases H4K12 and H3K9 histone acetylation in primary mouse neuronal cells. BRD6688 crosses the blood brain barrier and rescues the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model[1]. |
| Name | N-[2-Amino-5-(4-pyridinyl)phenyl]-1-pyrrolidinecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | BRD6688 is a selective HDAC2 inhibitor. BRD6688 increases H4K12 and H3K9 histone acetylation in primary mouse neuronal cells. BRD6688 crosses the blood brain barrier and rescues the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model[1]. |
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| Related Catalog | |
| Target |
HDAC2 |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 528.2±50.0 °C at 760 mmHg |
| Molecular Formula | C16H18N4O |
| Molecular Weight | 282.340 |
| Flash Point | 273.3±30.1 °C |
| Exact Mass | 282.148071 |
| LogP | 0.84 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.679 |
| N-[2-Amino-5-(4-pyridinyl)phenyl]-1-pyrrolidinecarboxamide |
| 1-Pyrrolidinecarboxamide, N-[2-amino-5-(4-pyridinyl)phenyl]- |