DYRKs-IN-1
Modify Date: 2025-09-10 19:49:34
DYRKs-IN-1 structure
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Common Name | DYRKs-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1387090-01-8 | Molecular Weight | 588.06 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H30ClN7O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DYRKs-IN-1DYRKs-IN-1 (Example 183) is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-1 has antitumor activity[1][2]. |
| Name | DYRKs-IN-1 |
|---|
| Description | DYRKs-IN-1 (Example 183) is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-1 has antitumor activity[1][2]. |
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| Related Catalog | |
| Target |
IC50: 9 nM (DYRK1B) and 5 nM (DYRK1A)[2] |
| In Vitro | DYRKs-IN-1 (compound 30) increases the cellular potency against the human colon tumor cell line SW 620 with an EC50 of 27 nM[2]. |
| References |
[1]. Kevin Anderson, et al. Pyrido pyrimidines. US20120184542A1 |
| Molecular Formula | C30H30ClN7O4 |
|---|---|
| Molecular Weight | 588.06 |