VXc-486
Modify Date: 2024-01-03 19:54:51
VXc-486 structure
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Common Name | VXc-486 | ||
|---|---|---|---|---|
| CAS Number | 1384984-18-2 | Molecular Weight | 428.460 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C21H25FN6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VXc-486VXc-486 is a gyrase B inhibitor, with bactericidal activity. VXc-486 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively[1]. |
| Name | VXc-486 |
|---|---|
| Synonym | More Synonyms |
| Description | VXc-486 is a gyrase B inhibitor, with bactericidal activity. VXc-486 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively[1]. |
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| Related Catalog | |
| Target |
gyrase B[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C21H25FN6O3 |
| Molecular Weight | 428.460 |
| Exact Mass | 428.197205 |
| LogP | 1.42 |
| Index of Refraction | 1.648 |
| Urea, N-ethyl-N'-[6-fluoro-5-[2-(1-hydroxy-1-methylethyl)-5-pyrimidinyl]-7-[(2R)-tetrahydro-2-furanyl]-1H-benzimidazol-2-yl]- |
| 1-Ethyl-3-{5-fluoro-6-[2-(2-hydroxy-2-propanyl)-5-pyrimidinyl]-4-[(2R)-tetrahydro-2-furanyl]-1H-benzimidazol-2-yl}urea |