Nω-Propyl-L-arginine
Modify Date: 2025-08-26 21:46:13
Nω-Propyl-L-arginine structure
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Common Name | Nω-Propyl-L-arginine | ||
|---|---|---|---|---|
| CAS Number | 137361-05-8 | Molecular Weight | 216.281 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 411.0±55.0 °C at 760 mmHg | |
| Molecular Formula | C9H20N4O2 | Melting Point | 122 °C(lit.) | |
| MSDS | N/A | Flash Point | 202.4±31.5 °C | |
Use of Nω-Propyl-L-arginineNω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. |
| Name | (2S)-2-amino-5-[(N'-propylcarbamimidoyl)amino]pentanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. |
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| Related Catalog | |
| In Vivo | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) (20 mg/kg; i.p.) blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity[2]. Animal Model: Male NMRI mice (30-40 g) (phencyclidine-induced stimulation)[2] Dosage: 20 mg/kg Administration: I.p. Result: Markedly reduced the phencyclidineinduced disruption of prepulse inhibition and significantly reduced the phencyclidine-induced stimulation of locomotor activity. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 411.0±55.0 °C at 760 mmHg |
| Melting Point | 122 °C(lit.) |
| Molecular Formula | C9H20N4O2 |
| Molecular Weight | 216.281 |
| Flash Point | 202.4±31.5 °C |
| Exact Mass | 216.158630 |
| PSA | 111.23000 |
| LogP | 0.11 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.550 |
| Storage condition | Desiccate at RT |
| Hazard Codes | C,O |
|---|---|
| Risk Phrases | R8:Contact with combustible material may cause fire. R34:Causes burns. |
| Safety Phrases | S26-S27-S36/37/39-S45-S17 |
| RIDADR | UN 3264 8/PG 2 |
| WGK Germany | 3 |
| Packaging Group | II |
| Hazard Class | 5.1 |
| HS Code | 2925290090 |
| HS Code | 2925290090 |
|---|---|
| Summary | 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
| N-(N'-Propylcarbamimidoyl)-L-ornithine |
| 3AR |
| Tocris-1200 |
| L-Ornithine, N-[(E)-amino(propylimino)methyl]- |
| MFCD01320455 |