Nomega-Allyl-L-arginine hydrochloride

Modify Date: 2024-01-10 17:04:31

Nomega-Allyl-L-arginine hydrochloride structure	Common Name	Nomega-Allyl-L-arginine hydrochloride
	CAS Number	139461-37-3	Molecular Weight	214.26500
	Density	1.23g/cm3	Boiling Point	394.4ºC at 760mmHg
	Molecular Formula	C₉H₁₈N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	192.3ºC

Use of Nomega-Allyl-L-arginine hydrochloride

Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS). Nω-allyl-L-arginine can inactivate nNOS in a time-dependent manner. Nω-allyl-L-arginine also is a substrate, producing L-arginine, acrolein, and H2O[1][2].

Name	(2S)-2-amino-5-[(N'-prop-2-enylcarbamimidoyl)amino]pentanoic acid
Synonym	More Synonyms

Description	Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS). Nω-allyl-L-arginine can inactivate nNOS in a time-dependent manner. Nω-allyl-L-arginine also is a substrate, producing L-arginine, acrolein, and H2O[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease
Target	nitric oxide synthase (nNOS)[1]
References	[1]. Zhang HQ, et, al. Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by Nω-Allyl-l-Arginine. J. Am. Chem. Soc. 1997, 119, 45, 10888-10902. [2]. Hah JM, et, al. Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase. Bioorg Med Chem. 2000 Aug;8(8):1931-6.

Density	1.23g/cm3
Boiling Point	394.4ºC at 760mmHg
Molecular Formula	C₉H₁₈N₄O₂
Molecular Weight	214.26500
Flash Point	192.3ºC
Exact Mass	214.14300
PSA	111.23000
LogP	1.06030
Vapour Pressure	2.54E-07mmHg at 25°C
Index of Refraction	1.549