UK-78282 Hydrochloride
Modify Date: 2024-01-30 13:17:32
UK-78282 Hydrochloride structure
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Common Name | UK-78282 Hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 136647-02-4 | Molecular Weight | 466.05 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H36ClNO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of UK-78282 HydrochlorideUK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC50 of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil[1]. |
| Name | 4-(benzhydryloxymethyl)-1-[3-(4-methoxyphenyl)propyl]piperidine,hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | UK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC50 of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil[1]. |
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| Related Catalog | |
| Target |
IC50: 200 nM (Kv1.3)[1] |
| References |
| Molecular Formula | C29H36ClNO2 |
|---|---|
| Molecular Weight | 466.05 |
| Exact Mass | 465.24300 |
| PSA | 21.70000 |
| LogP | 6.88590 |
| Storage condition | -20°C |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319-H400 |
| Precautionary Statements | P273-P305 + P351 + P338 |
| RIDADR | UN 3077 9 / PGIII |
| HS Code | 2933399090 |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidinehydrochloride |
| 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidine monohydrochloride |