BIM-26226

Modify Date: 2025-08-29 11:41:13

BIM-26226 Structure
BIM-26226 structure
Common Name BIM-26226
CAS Number 136207-23-3 Molecular Weight 1075.09
Density N/A Boiling Point N/A
Molecular Formula C49H63F5N12O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BIM-26226


BIM-26226, gastrin-releasing peptide, is a potent and selective antagonist of bombesin receptor. BIM-26226 inhibits BN- or GRP-stimulated amylase release with IC50s in the nanomolar range. BIM-26226 can be used for the research of cancer[1][2].

 Names

Name BIM-26226

 BIM-26226 Biological Activity

Description BIM-26226, gastrin-releasing peptide, is a potent and selective antagonist of bombesin receptor. BIM-26226 inhibits BN- or GRP-stimulated amylase release with IC50s in the nanomolar range. BIM-26226 can be used for the research of cancer[1][2].
Related Catalog
Target

bombesin receptor[1]

References

[1]. Dietrich JB, et, al. Effects of BIM26226, a potent and specific bombesin receptor antagonist, on amylase release and binding of bombesin-like peptides to AR4-2J cells. Regul Pept. 1994 Oct 21;53(3):165-73.

[2]. Damgé C, et, al. Effect of the gastrin-releasing peptide antagonist BIM 26226 and lanreotide on an acinar pancreatic carcinoma. Eur J Pharmacol. 1998 Apr 17;347(1):77-86.

 Chemical & Physical Properties

Molecular Formula C49H63F5N12O10
Molecular Weight 1075.09
InChIKey ZCTCXFYZJYFGAQ-ZZXDJSGYSA-N
SMILES COC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(C)NC(=O)C(NC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)C(N)Cc1c(F)c(F)c(F)c(F)c1F)C(C)C
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