150155-61-6

150155-61-6 structure

Name: BIM 23056
Chemical Name: D-Phe-Phe-Tyr-D-Trp-Lys-Val-Phe-3-(2-naphthalenyl)-D-Ala-NH2
CAS Number: 150155-61-6
Molecular Formula: C₇₁H₈₁N₁₁O₉
Molecular Weight: 1232.47000
Catalog: Signaling Pathways GPCR/G Protein Somatostatin Receptor
Create Date: 2017-01-19 14:03:55
Modify Date: 2024-01-08 14:12:54
BIM 23056, a linear octapeptide, is a potent sst3 and sst5 somatostatin receptor antagonist with Ki values of 10.8, 5.7, respectively[1].

Name	D-Phe-Phe-Tyr-D-Trp-Lys-Val-Phe-3-(2-naphthalenyl)-D-Ala-NH2
Synonyms	D-2-Phenylglycine Donitriptan hydrochloride D-Phe-ol hydrochloride D-Phe-Phe-Tyr-D-Trp-Lys-Val-Phe-D-Nal-NH2 D-PHENYLGLYCINE H-D-PHG-OH

Description	BIM 23056, a linear octapeptide, is a potent sst3 and sst5 somatostatin receptor antagonist with Ki values of 10.8, 5.7, respectively[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor Research Areas >> Neurological Disease
In Vitro	BIM 23056 has Ki values of 142, 16.6, >1000 for sst1, sst4, sst2 , respectively[1].
References	[1]. Y C Patel, et al. Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5). Endocrinology. 1994 Dec;135(6):2814-7. [2]. W Feniuk, et al. Further evidence from functional studies for somatostatin receptor heterogeneity in guinea-pig isolated ileum, vas deferens and right atrium. Br J Pharmacol. 1995 Jul;115(6):975-80.