136207-23-3

136207-23-3 structure

Name: BIM-26226
Chemical Name: BIM-26226
CAS Number: 136207-23-3
Molecular Formula: C₄₉H₆₃F₅N₁₂O₁₀
Molecular Weight: 1075.09
Catalog: Signaling Pathways GPCR/G Protein Bombesin Receptor
Create Date: 2022-03-25 21:27:25
Modify Date: 2025-08-29 11:41:13
BIM-26226, gastrin-releasing peptide, is a potent and selective antagonist of bombesin receptor. BIM-26226 inhibits BN- or GRP-stimulated amylase release with IC50s in the nanomolar range. BIM-26226 can be used for the research of cancer[1][2].

Name	BIM-26226

Description	BIM-26226, gastrin-releasing peptide, is a potent and selective antagonist of bombesin receptor. BIM-26226 inhibits BN- or GRP-stimulated amylase release with IC50s in the nanomolar range. BIM-26226 can be used for the research of cancer[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Bombesin Receptor
Target	bombesin receptor[1]
References	[1]. Dietrich JB, et, al. Effects of BIM26226, a potent and specific bombesin receptor antagonist, on amylase release and binding of bombesin-like peptides to AR4-2J cells. Regul Pept. 1994 Oct 21;53(3):165-73. [2]. Damgé C, et, al. Effect of the gastrin-releasing peptide antagonist BIM 26226 and lanreotide on an acinar pancreatic carcinoma. Eur J Pharmacol. 1998 Apr 17;347(1):77-86.

Molecular Formula	C₄₉H₆₃F₅N₁₂O₁₀
Molecular Weight	1075.09