Acetamiprid

Modify Date: 2024-01-02 17:38:34

Acetamiprid structure	Common Name	Acetamiprid
	CAS Number	135410-20-7	Molecular Weight	222.674
	Density	1.2±0.1 g/cm3	Boiling Point	352.4±52.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₁ClN₄	Melting Point	101-103ºC
	MSDS	Chinese USA	Flash Point	166.9±30.7 °C
	Symbol	GHS06	Signal Word	Danger

Use of Acetamiprid

Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders[1][2].

Name	(E)-acetamiprid
Synonym	More Synonyms

Description	Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	nAChR[1]
In Vivo	Acetamiprid decreases in body weight and mildly affected spermatogenesis. [1]. Acetamiprid decreases the expression of testosterone-metabolism genes, nAChR subunit genes, and proliferation-associated genes in mice[1]. Acetamiprid disrupts subsequent testosterone biosynthesis by decreasing the rate of conversion of cholesterol to testosterone and by preventing cholesterol from entering the mitochondria within the Leydig cells. These effects caused reproductive damage to the rats[2]. Animal Model: Male Sprague Dawley (SD) rats[2] Dosage: 10 mg/kg, 30 mg/kg Administration: Oral gavage; daily; for 35 days Result: Inhibited testosterone synthesis by affecting the mitochondrial function and cytoplasmic adenosine triphosphate production in rat Leydig cells.
References	[1]. Terayama H, et al. Effect of acetamiprid on the immature murine testes. Int J Environ Health Res. 2018 Dec;28(6):683-696. [2]. Kong D, et al. Acetamiprid inhibits testosterone synthesis by affecting the mitochondrial function and cytoplasmic adenosine triphosphate production in rat Leydig cells. Biol Reprod. 2017 Jan 1;96(1):254-265.

Density	1.2±0.1 g/cm3
Boiling Point	352.4±52.0 °C at 760 mmHg
Melting Point	101-103ºC
Molecular Formula	C₁₀H₁₁ClN₄
Molecular Weight	222.674
Flash Point	166.9±30.7 °C
Exact Mass	222.067230
PSA	52.28000
LogP	0.62
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.571
Storage condition	0-6°C

Acetamiprid MSDS(Chinese)

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H330-H412
Precautionary Statements	P260-P273-P284-P301 + P310-P310
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;
Risk Phrases	R23/25;R57
Safety Phrases	S45
RIDADR	UN 2811
RTECS	KJ4235200
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933399022

HS Code	2933399022
Summary	2933399022 1,1'-dimethyl-[4,4'-bipyridine]-1,1'-diium。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Capillary electrophoresis-mass spectrometry as a new approach to analyze neonicotinoid insecticides.

J. Chromatogr. A. 1359 , 317-24, (2014)

This paper represents the first report of a capillary electrophoresis (CE) method compatible with mass spectrometry (MS) detection for simultaneously analyzing seven neonicotinoid insecticides (acetam...

Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth-assisted extraction and liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 969 , 85-94, (2014)

A rapid and sensitive analytical method was developed for simultaneous determination of eight neonicotinoid insecticides (acetamiprid, clothianidin, dinotefuran, flonicamid, imidacloprid, nitenpyram, ...

Development of a new cucumber reference material for pesticide residue analysis: feasibility study for material processing, homogeneity and stability assessment.

Anal. Bioanal. Chem 407(11) , 3083-91, (2015)

The feasibility of the production of a reference material for pesticide residue analysis in a cucumber matrix was investigated. Cucumber was spiked at 0.075 mg/kg with each of the 15 selected pesticid...

(1E)-N-[(6-chloro-3-pyridinyl)methyl]-N’-cyano-N-methylethanimidamide

(E)-N-[(6-Chloropyridin-3-yl)methyl]-N'-cyano-N-methylacetimidamide

(E)-N1-[(6-Chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine

(E)-N-((6-Chloropyridin-3-yl)methyl)-N'-cyano-N-methylacetimidamide

acetamiprid

(1E)-N-[(6-Chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide

(E)-N-(6-Chloro-3-pyridylmethyl)-N'-cyano-N-methylacetamidine

(E)-N-[(6-Chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide

Ethanimidamide, N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methyl-, (1E)-

(1E)-N-[(6-chloropyridin-3-yl)methyl]-N’-cyano-N-methylethanimidamide

N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide

MFCD06201842

(1E)-N-[(6-Chlorpyridin-3-yl)methyl]-N'-cyan-N-methylethanimidamid

T6NJ BG E1N1Y1&UNCN &&E Form

(1E)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Acetamiprid
Price: ￥608.0/100mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Intruder
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Acetamiprid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: GIOVANNI PAPAGNI
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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