T338C Src-IN-2

Modify Date: 2024-01-12 11:43:38

T338C Src-IN-2 Structure
T338C Src-IN-2 structure
Common Name T338C Src-IN-2
CAS Number 1351927-00-8 Molecular Weight 327.356
Density 1.4±0.1 g/cm3 Boiling Point 540.6±50.0 °C at 760 mmHg
Molecular Formula C17H18FN5O Melting Point N/A
MSDS N/A Flash Point 280.8±30.1 °C

 Use of T338C Src-IN-2


T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.

 Names

Name T338C Src-IN-2
Synonym More Synonyms

 T338C Src-IN-2 Biological Activity

Description T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.
Related Catalog
References

[1]. Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15046-52.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 540.6±50.0 °C at 760 mmHg
Molecular Formula C17H18FN5O
Molecular Weight 327.356
Flash Point 280.8±30.1 °C
Exact Mass 327.149536
LogP 1.54
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.657
Storage condition 2-8℃

 Synonyms

1-{3-[(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl]phenyl}-2-fluoroethanone
Ethanone, 1-[3-[[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]phenyl]-2-fluoro-
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