Propargyl-PEG3-acid
Modify Date: 2025-08-27 09:19:12
Propargyl-PEG3-acid structure
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Common Name | Propargyl-PEG3-acid | ||
|---|---|---|---|---|
| CAS Number | 1347760-82-0 | Molecular Weight | 216.231 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 348.0±32.0 °C at 760 mmHg | |
| Molecular Formula | C10H16O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 131.8±18.6 °C | |
Use of Propargyl-PEG3-acidPropargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid[1]. |
| Name | 3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid[1]. |
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| Related Catalog | |
| Target |
PEGs Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 348.0±32.0 °C at 760 mmHg |
| Molecular Formula | C10H16O5 |
| Molecular Weight | 216.231 |
| Flash Point | 131.8±18.6 °C |
| Exact Mass | 216.099777 |
| LogP | -0.44 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.467 |
| Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]- |
| 3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoic acid |