2055024-44-5

2055024-44-5 structure

2055024-44-5 structure

Name: Propargyl-peg3-sulfone-peg3-propargyl
Chemical Name: Propargyl-peg3-sulfone-peg3-propargyl
CAS Number: 2055024-44-5
Molecular Formula: C₂₂H₃₈O₁₀S
Molecular Weight: 494.60
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:43:10
Modify Date: 2024-01-16 16:09:38
Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-peg3-sulfone-peg3-propargyl
Synonyms	MFCD30182062

Description	Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₂H₃₈O₁₀S
Molecular Weight	494.60