α2β1 Integrin Recognition Sequence
α2β1 Integrin Recognition Sequence structure
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Common Name | α2β1 Integrin Recognition Sequence | ||
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| CAS Number | 134580-64-6 | Molecular Weight | 390.34600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H22N4O9 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of α2β1 Integrin Recognition Sequenceα2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1]. |
| Name | (4S)-4-[[2-[[(2S)-2-amino-3-carboxypropanoyl]amino]acetyl]amino]-5-[[(1S)-1-carboxyethyl]amino]-5-oxopentanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C14H22N4O9 |
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| Molecular Weight | 390.34600 |
| Exact Mass | 390.13900 |
| PSA | 235.69000 |
| LogP | 0.06470 |
| RIDADR | NONH for all modes of transport |
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Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.
J. Biol. Chem. 266 , 7363-7367, (1991) The alpha 2 beta 1 integrin serves as either a specific cell surface receptor for collagen or as both a collagen and laminin receptor depending upon the cell type. Recently we established that the alp... |
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RGDS and DGEA-induced [Ca2+]i signalling in human dermal fibroblasts.
Biochim. Biophys. Acta Mol. Cell Res. 1746(1) , 28-37, (2005) A pulse of short peptides, RGDS and DGEA in the millimolar range, immediately elicits in normal human fibroblasts a transient increase of intracellular Ca2+ ([Ca2+]i). In the present study, we show th... |
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Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV.
PLoS ONE 8 , e59558, (2013) Glioma initiating cells (GICs) are considered responsible for the therapeutic resistance and recurrence of malignant glioma. To clarify the molecular mechanism of GIC maintenance/differentiation, we e... |
| L-|A-Aspartylglycyl-L-|A-glutamyl-L-alanine |
| |A2|A1 Integrin Recognition Sequence |
| H-Asp-Gly-Glu-Ala-OH |
| DGEA |