αvβ1 integrin-IN-1

Modify Date: 2025-08-24 21:40:10

αvβ1 integrin-IN-1 Structure
αvβ1 integrin-IN-1 structure
 Common Name αvβ1 integrin-IN-1
CAS Number 1689540-62-2 Molecular Weight 558.65
Density N/A Boiling Point N/A
Molecular Formula C26H34N6O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of αvβ1 integrin-IN-1


αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].

 Names

Name αvβ1 integrin-IN-1

 αvβ1 integrin-IN-1 Biological Activity

Description αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].
Related Catalog
Target

IC50: 0.63 nM (αvβ1 integrin)[1]

In Vitro αvβ1 integrin-IN-1 (Compound C8) significantly reduces the fibrotic markers in mouse model for liver and lung fibrosis[1].
References

[1]. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett. 2016 Aug 30;7(10):902-907.

 Chemical & Physical Properties

Molecular Formula C26H34N6O6S
Molecular Weight 558.65
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