DC Chemicals Limited
China
Product Name: αvβ1 integrin-IN-1
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Purity: 98.0%
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Contact: Tony Cao

1689540-62-2

1689540-62-2 structure

1689540-62-2 structure

Name: αvβ1 integrin-IN-1
Chemical Name: αvβ1 integrin-IN-1
CAS Number: 1689540-62-2
Molecular Formula: C₂₆H₃₄N₆O₆S
Molecular Weight: 558.65
Catalog: Signaling Pathways Cytoskeleton Integrin
Create Date: 2020-01-23 13:21:51
Modify Date: 2024-01-12 08:42:18
αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].

Name	αvβ1 integrin-IN-1

Description	αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Cytoskeleton >> Integrin
Target	IC50: 0.63 nM (αvβ1 integrin)[1]
In Vitro	αvβ1 integrin-IN-1 (Compound C8) significantly reduces the fibrotic markers in mouse model for liver and lung fibrosis[1].
References	[1]. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett. 2016 Aug 30;7(10):902-907.

Molecular Formula	C₂₆H₃₄N₆O₆S
Molecular Weight	558.65