RKI-1313
Modify Date: 2024-01-03 17:00:22
RKI-1313 structure
|
Common Name | RKI-1313 | ||
|---|---|---|---|---|
| CAS Number | 1342276-76-9 | Molecular Weight | 340.400 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C17H16N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RKI-1313RKI-1313 is a ROCK inhibitor with IC50s of 34, 8 µM for ROCK 1 and ROCK 2, respectively. RKI-1313 shows little effect on the phosphorylation levels of ROCK substrates, migration, invasion or anchorage-independent growth[1]. |
| Name | 1-(3-methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea |
|---|---|
| Synonym | More Synonyms |
| Description | RKI-1313 is a ROCK inhibitor with IC50s of 34, 8 µM for ROCK 1 and ROCK 2, respectively. RKI-1313 shows little effect on the phosphorylation levels of ROCK substrates, migration, invasion or anchorage-independent growth[1]. |
|---|---|
| Related Catalog | |
| Target |
ROCK1:34 μM (IC50) ROCK2:8 μM (IC50) |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C17H16N4O2S |
| Molecular Weight | 340.400 |
| Exact Mass | 340.099396 |
| PSA | 104.38000 |
| LogP | 2.08 |
| Index of Refraction | 1.655 |
| Storage condition | -20℃ |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
CAS#:1342278-01-6| 1-(3-Methoxybenzyl)-3-[4-(pyridin-4-yl)thiazol-2-yl]urea |
| 1-(3-Methoxybenzyl)-3-[4-(4-pyridinyl)-1,3-thiazol-2-yl]urea |
| Urea, N-[(3-methoxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]- |
| RKI-1313 |