PF-4840154

Modify Date: 2025-08-23 14:29:00

PF-4840154 structure	Common Name	PF-4840154
	CAS Number	1332708-14-1	Molecular Weight	466.619
	Density	1.2±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₈N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PF-4840154

PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC50s of 97 and 23 nM, respectively.

Name	PF-4840154
Synonym	More Synonyms

Description	PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC50s of 97 and 23 nM, respectively.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Inflammation/Immunology
Target	IC50: 97 nM (rTrpA1), 23 nM (hTrpA1)[1]
References	[1]. Ryckmans T, et al. Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4857-4859.

Density	1.2±0.1 g/cm3
Molecular Formula	C₂₆H₃₈N₆O₂
Molecular Weight	466.619
Exact Mass	466.305634
LogP	6.03
Index of Refraction	1.589
Storage condition	2-8℃

PF-4840154

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China
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: PF-4840154
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DC Chemicals Limited
China
Product Name: PF-4840154
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-Pyrimidinecarboxamide, 4-[(2-Methylpropyl)amino]-N-(phenylmethyl)-2-[4-[(tetrahydro-2H-pyran-3-yl)Methyl]-1-piperazinyl]-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: $462/10mM*1mLinDMSO

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