Trypanothione synthetase-IN-3
Modify Date: 2025-08-25 15:48:32
Trypanothione synthetase-IN-3 structure
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Common Name | Trypanothione synthetase-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 1314875-96-1 | Molecular Weight | 1559.13 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C68H54O43 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Trypanothione synthetase-IN-3Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum[1]. |
| Name | Trypanothione synthetase-IN-3 |
|---|
| Description | Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum[1]. |
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| Related Catalog | |
| Target |
Trypanothione synthetase (TryS)[1] |
| In Vitro | Trypanothione synthetase-IN-3 (30 min) displays noncompetitive inhibitory behavior against Li TryS with IC50 values of 2 μM -5.6 μM (determined by various substrates)[1]. Trypanothione synthetase-IN-3 (24 h) inhibits proliferation of L. infantum axenic amastigotes with an EC50 value of 43.7 μM[1]. |
| References |
| Molecular Formula | C68H54O43 |
|---|---|
| Molecular Weight | 1559.13 |
| InChIKey | LVWJZBHMFBYXBN-UUTZMJNCSA-N |
| SMILES | O=C(OCC1OC(OC2OC(COC(=O)c3cc(O)c(O)c(O)c3)C(OC(=O)c3cc(O)c(O)c(O)c3)C(OC(=O)c3cc(O)c(O)c(O)c3)C2OC(=O)c2cc(O)c(O)c(O)c2)C(OC(=O)c2cc(O)c(O)c(O)c2)C(OC(=O)c2cc(O)c(O)c(O)c2)C1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 |