Name | Trypanothione synthetase-IN-3 |
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Description | Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum[1]. |
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Related Catalog | |
Target |
Trypanothione synthetase (TryS)[1] |
In Vitro | Trypanothione synthetase-IN-3 (30 min) displays noncompetitive inhibitory behavior against Li TryS with IC50 values of 2 μM -5.6 μM (determined by various substrates)[1]. Trypanothione synthetase-IN-3 (24 h) inhibits proliferation of L. infantum axenic amastigotes with an EC50 value of 43.7 μM[1]. |
References |
Molecular Formula | C68H54O43 |
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Molecular Weight | 1559.13 |