Tubulin inhibitor 8
Modify Date: 2024-01-22 16:24:00
Tubulin inhibitor 8 structure
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Common Name | Tubulin inhibitor 8 | ||
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| CAS Number | 1309925-39-0 | Molecular Weight | 342.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H14N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tubulin inhibitor 8Tubulin inhibitor 8 (Compound 33b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 8 inhibits tubulin polymerization with an IC50 of 0.73 μM. Tubulin inhibitor 8 inhibits K562 cell growth with an IC50 of 14 nM[1]. |
| Name | Tubulin inhibitor 8 |
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| Description | Tubulin inhibitor 8 (Compound 33b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 8 inhibits tubulin polymerization with an IC50 of 0.73 μM. Tubulin inhibitor 8 inhibits K562 cell growth with an IC50 of 14 nM[1]. |
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| Related Catalog | |
| Target |
IC50: 0.73 μM (tubulin polymerization)[1] |
| In Vitro | Tubulin inhibitor 8 blocks mitosis through an arrest of cells in the G2/M phase, as illustrated in typical histograms[1]. Tubulin inhibitor 8 shows excellent antiproliferative potencies with IC50s of 15, 6, 8, 2, 8, 6, and 9 nM for NCIH460, SKOV3, BT549, 451LU, SW480, COLO-205, and DLD-1 tumor cell lines, recpectively[1]. |
| References |
| Molecular Formula | C21H14N2O3 |
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| Molecular Weight | 342.35 |
| Hazard Codes | Xi |
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