PLX5622

Modify Date: 2025-08-25 20:26:37

PLX5622 Structure
PLX5622 structure
Common Name PLX5622
CAS Number 1303420-67-8 Molecular Weight 395.41
Density N/A Boiling Point N/A
Molecular Formula C21H19F2N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PLX5622


PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals[1].

 Names

Name PLX5622

 PLX5622 Biological Activity

Description PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals[1].
Related Catalog
Target

CSF1R[1].

References

[1]. Spangenberg E, et al. Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun. 2019 Aug 21;10(1):3758.

 Chemical & Physical Properties

Molecular Formula C21H19F2N5O
Molecular Weight 395.41
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