(+)-Igmesine hydrochloride

Modify Date: 2024-02-06 10:05:11

(+)-Igmesine hydrochloride Structure
(+)-Igmesine hydrochloride structure
Common Name (+)-Igmesine hydrochloride
CAS Number 130152-35-1 Molecular Weight 355.94
Density 1.027g/cm3 Boiling Point 445.1ºC at 760mmHg
Molecular Formula C23H30ClN Melting Point N/A
MSDS N/A Flash Point 196.9ºC

 Use of (+)-Igmesine hydrochloride


(+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ receptor ligand with neuroprotective and anti-amnesic activities[1].

 Names

Name (E)-N-(cyclopropylmethyl)-N-methyl-3,6-diphenylhex-5-en-3-amine,hydrochloride
Synonym More Synonyms

 (+)-Igmesine hydrochloride Biological Activity

Description (+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ receptor ligand with neuroprotective and anti-amnesic activities[1].
Related Catalog
References

[1]. O'Neill M, et al. The sigma receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia. Eur J Pharmacol. 1995 Sep 5;283(1-3):217-25.  

 Chemical & Physical Properties

Density 1.027g/cm3
Boiling Point 445.1ºC at 760mmHg
Molecular Formula C23H30ClN
Molecular Weight 355.94
Flash Point 196.9ºC
Exact Mass 355.20700
PSA 3.24000
LogP 6.53920

 Synonyms

Cinnamyl-1-phenyl-1-N-methyl-N-cyclopropylene
JO-1784
Igmesine hydrochloride
Sipatrigine
CI-1019