130152-35-1

130152-35-1 structure

Name: (+)-Igmesine hydrochloride
Chemical Name: (E)-N-(cyclopropylmethyl)-N-methyl-3,6-diphenylhex-5-en-3-amine,hydrochloride
CAS Number: 130152-35-1
Molecular Formula: C₂₃H₃₀ClN
Molecular Weight: 355.94
Catalog: Signaling Pathways GPCR/G Protein Sigma Receptor
Create Date: 2016-11-10 08:24:34
Modify Date: 2025-11-06 13:23:51
(+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ receptor ligand with neuroprotective and anti-amnesic activities[1].

Name	(E)-N-(cyclopropylmethyl)-N-methyl-3,6-diphenylhex-5-en-3-amine,hydrochloride
Synonyms	Cinnamyl-1-phenyl-1-N-methyl-N-cyclopropylene JO-1784 Igmesine hydrochloride Sipatrigine CI-1019

Description	(+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ receptor ligand with neuroprotective and anti-amnesic activities[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Sigma Receptor
References	[1]. O'Neill M, et al. The sigma receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia. Eur J Pharmacol. 1995 Sep 5;283(1-3):217-25.