Rifaximin-d6

Modify Date: 2025-08-24 20:05:14

Rifaximin-d6 structure	Common Name	Rifaximin-d6
	CAS Number	1262992-43-7	Molecular Weight	791.916
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₃H₄₅D₆N₃O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Rifaximin-d6

Rifaximin-d6 is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity[1][2].

Name	Rifaximin-d6
Synonym	More Synonyms

Description	Rifaximin-d6 is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Cruciani F, Brigidi P, Calanni F et al. Efficacy of rifaximin vaginal tablets in treatment of bacterial vaginosis: a molecular characterization of the vaginal microbiota. Antimicrob Agents Chemother. 2012 Aug;56(8):4062-70. [3]. Cremonini F, Lembo A. Rifaximin for the treatment of irritable bowel syndrome. Expert Opin Pharmacother. 2012 Feb;13(3):433-40. [4]. Rivkin A, Gim S. Rifaximin: new therapeutic indication and future directions. Clin Ther. 2011 Jul;33(7):812-27. [5]. Cottreau J, Baker SF, DuPont HL, Garey KW. Rifaximin: a nonsystemic rifamycin antibiotic for gastrointestinal infections. Expert Rev Anti Infect Ther. 2010 Jul;8(7):747-60. [6]. Koo HL, DuPont HL. Rifaximin: a unique gastrointestinal-selective antibiotic for enteric diseases. Curr Opin Gastroenterol. 2010 Jan;26(1):17-25. [7]. Ojetti V, Lauritano EC, Barbaro F et al. Rifaximin pharmacology and clinical implications. Expert Opin Drug Metab Toxicol. 2009 Jun;5(6):675-82.

Density	1.4±0.1 g/cm3
Molecular Formula	C₄₃H₄₅D₆N₃O₁₁
Molecular Weight	791.916
Exact Mass	791.390015
LogP	3.22
Index of Refraction	1.634

2,7-(Epoxy[1,11,13]pentadecatrienoimino)furo[2'',3'':7',8']naphth[1',2':4,5]imidazo[1,2-a]pyridine-1,15(2H)-dione-9,10,12-d3, 25-(acetyloxy)-5,6,21,23-tetrahydroxy-27-methoxy-2,4,16,20,22,24,26-hept amethyl-11-(methyl-d3)-, (2S,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-

(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,36-Tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30-(2H3)methyl-6,23-dioxo(28,29,31-2H3)-8,37-dioxa-24,27,33-triazahexacyclo[23 .10.1.14,7.05,35.026,34.027,32]heptatriaconta-1(35),2,4,9,19,21,25(36),26(34),28,30,32-undecaen-13-yl acetate

RIFAXIMIN-D6

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Rifaximin-d6

Use of Rifaximin-d6

Names

Rifaximin-d6 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.