LEE011-D6

Modify Date: 2025-08-25 12:20:33

LEE011-D6 Structure
LEE011-D6 structure
Common Name LEE011-D6
CAS Number 1328934-40-2 Molecular Weight 440.57
Density N/A Boiling Point N/A
Molecular Formula C23H24D6N8O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LEE011-D6


Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].

 Names

Name Ribociclib D6

 LEE011-D6 Biological Activity

Description Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].
Related Catalog
References

[1]. VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1;21(13):2905-10.

 Chemical & Physical Properties

Molecular Formula C23H24D6N8O
Molecular Weight 440.57
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

LEE011-D6 suppliers

LEE011-D6 price