Icariside E5

Modify Date: 2024-01-03 18:33:07

Icariside E5 structure	Common Name	Icariside E5
	CAS Number	126176-79-2	Molecular Weight	522.542
	Density	1.4±0.1 g/cm3	Boiling Point	807.6±65.0 °C at 760 mmHg
	Molecular Formula	C₂₆H₃₄O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	442.2±34.3 °C

Use of Icariside E5

Icariside E5 is a lignan glycoside isolated from the Albiziae Cortex. Icariside E5 promotes the proliferation of HUVECs without cytotoxicity. Icariside E5 has antioxidant properties[1][2].

Name	2-[(2R)-1-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-propanyl]-4-[(1 E)-3-hydroxy-1-propen-1-yl]-6-methoxyphenyl β-D-glucopyranoside
Synonym	More Synonyms

Description	Icariside E5 is a lignan glycoside isolated from the Albiziae Cortex. Icariside E5 promotes the proliferation of HUVECs without cytotoxicity. Icariside E5 has antioxidant properties[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Icariside E5 (5, 10, 20, 40 µM; for 48 h) slightly promotes the proliferation of human umbilical vein endothelial cells (HUVECs). Icariside E5 does not have the pharmacological effect of scavenging ROS[1]. Icariside E neither induces an increase in the intracellular levels of reactive oxygen species nor affects the mitochondria permeability transition, and it does not signal through the vanilloid receptor type 1. It protects Jurkat cells from apoptosis induced by the oxidative stress mediated by serum withdrawal[2].
References	[1]. Xuelin Shi, et al. Chemical Constituents from Albiziae Cortex and Their Ability to Ameliorate Steatosis and Promote Proliferation and Anti-Oxidation In Vitro. Molecules. 2019 Nov 7;24(22):4041. [2]. M Iorizzi, et al. New glycosides from Capsicum annuum L. var. acuminatum. Isolation, structure determination, and biological activity. J Agric Food Chem. 2001 Apr;49(4):2022-9.

Density	1.4±0.1 g/cm3
Boiling Point	807.6±65.0 °C at 760 mmHg
Molecular Formula	C₂₆H₃₄O₁₁
Molecular Weight	522.542
Flash Point	442.2±34.3 °C
Exact Mass	522.210083
PSA	178.53000
LogP	-1.42
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.650

Hazard Codes	Xi

β-D-Glucopyranoside, 2-[(1R)-2-hydroxy-1-[(4-hydroxy-3-methoxyphenyl)methyl]ethyl]-4-[(1E)-3-hydroxy-1-propen-1-yl]-6-methoxyphenyl

icariside E5

Icariside E5

BioBioPha
China
Product Name: Icariside E5
Price: ￥3900.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Icariside E5
Price: ￥5280.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ICARISIDE E5
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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