115009-57-9

115009-57-9 structure

Name: Icariside F2
Chemical Name: icariside F2
CAS Number: 115009-57-9
Molecular Formula: C₁₈H₂₆O₁₀
Molecular Weight: 402.39300
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-08-09 11:35:31
Modify Date: 2024-01-03 14:24:28
Icariside F2 is a potent NF-κB inhibitor with an IC50 value of 16.25 μM. Icariside F2 is an aromatic glycoside isolated from the leaves of E. ulmoides Oliver. Icariside F2 has anti-inflammatory activity[1].

Name	icariside F2
Synonyms	(2R,3R,4S,5S,6R)-2-Benzyloxy-6-((2R,3R,4S)-3,4-dihydroxy-4-hydroxymethyl-tetrahydro-furan-2-yloxymethyl)-tetrahydro-pyran-3,4,5-triol

Description	Icariside F2 is a potent NF-κB inhibitor with an IC50 value of 16.25 μM. Icariside F2 is an aromatic glycoside isolated from the leaves of E. ulmoides Oliver. Icariside F2 has anti-inflammatory activity[1].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	NF-κB:16.25 μM (IC50)
In Vitro	At a concentration of 10 μΜ, Icariside F2 shows little or no cytotoxic activity by the MTT assay[1].
References	[1]. Meng-Meng Bai, et al. Soluble epoxide hydrolase inhibitory and anti-inflammatory components from the leaves of Eucommia ulmoides Oliver (duzhong). J Agric Food Chem. 2015 Mar 4;63(8):2198-205.