Biotin-PEG4-amino-t-Bu-DADPS-C6-azide

Modify Date: 2025-08-25 17:57:48

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide structure	Common Name	Biotin-PEG4-amino-t-Bu-DADPS-C6-azide
	CAS Number	1260247-50-4	Molecular Weight	886.18
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₃H₆₇N₇O₉SSi	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Biotin-PEG4-amino-t-Bu-DADPS-C6-azide

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG4-amino-t-Bu-DADPS-C6-azide

Description	Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₃H₆₇N₇O₉SSi
Molecular Weight	886.18
InChIKey	CSHHHVOFXKFHMG-OJXHMOJOSA-N
SMILES	CC(C)(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCCC1SCC2NC(=O)NC21)O[Si](OCCCCCCN=[N+]=[N-])(c1ccccc1)c1ccccc1

Hazard Codes	Xi

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