Biotin-PEG4-azide structure
|
Common Name | Biotin-PEG4-azide | ||
|---|---|---|---|---|
| CAS Number | 1309649-57-7 | Molecular Weight | 488.601 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H36N6O6S | Melting Point | 104 °C | |
| MSDS | N/A | Flash Point | N/A | |
Use of Biotin-PEG4-azideBiotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | Biotin-PEG4-Azide |
|---|---|
| Synonym | More Synonyms |
| Description | Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Melting Point | 104 °C |
|---|---|
| Molecular Formula | C20H36N6O6S |
| Molecular Weight | 488.601 |
| Exact Mass | 488.241699 |
| LogP | -1.28 |
| InChIKey | PVEHVEYAPUNCCP-LNLFQRSKSA-N |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCNC(=O)CCCCC1SCC2NC(=O)NC21 |
| N-(14-Azido-3,6,9,12-tetraoxatetradec-1-yl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide |
| MFCD27977501 |
| 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(14-azido-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)- |